Interaction of Magnetite Nanaparticles with Culture of Alveolar Macrophages at Different Protein Concentrations

1Kiroshka, VV, 1Samchenko, II, 2Nadutov, VM, 2Perekos, AYe., 2Voynash, VZ, 1Bondarenko, TP
1Institute for Problems of Cryobiology and Cryomedicine, NAS of Ukraine, Kharkiv
2G.V. Kurdyumov Institute for Metal Physics, NAS of Ukraine, Kyiv
Nauka innov. 2011, 7(6):44-49
https://doi.org/10.15407/scin7.06.044
Section: Scientific Basis of Innovation Activity
Language: Russian
Abstract: 
The interactions of magnetite (Fe3O4) nanoparticles within the concentration range 0.06÷1.8 mg/ml with the culture of alveolar macrophages in presence of 10 and 20% FBS were comparatively analyzed. It has been established that the rise in protein content in incubation medium resulted in increase of nanoparticle number able to interact with cells.
Keywords: cell culture, cytotoxicity, magnetite (Fe3O4) nanoparticles
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