Mechanisms of Weak Magnetic Field Influence on Gene Expression: Basics of Physical Epigenetics

TitleMechanisms of Weak Magnetic Field Influence on Gene Expression: Basics of Physical Epigenetics
Publication TypeJournal Article
Year of Publication2011
AuthorsZaporozhan, VM, Ponomarenko, AI
Short TitleNauka innov.
SectionScientific Basis of Innovation Activity
According to the developed theory, proteins of the Cryptochrome family (CRY) are the primary magnetic field acceptor in the cell genome. These proteins are known as repressors of the major circadian transcriptional complex CLOCK/BMAL1. The mechanism described allows magnetic field to perform bioregulation functions on genome level. The magnetic field-mediated bioregulation isable to influence human health and may have epidemiological, evolutionary, climate-regulatory and ot her global consequences for biosphere.
Keywordscircadian rhythms, Cryptochrome, electromagnetic field, gene expression, NF-κB, radical pairs, transcription
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